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What comes out of your research depends in large part on what goes into your research models. Ensuring your study animals have the most appropriate diet is critical to maintaining consistent, reliable research data. Download growth curve. Envigo uses well-established techniques to successfully produce time mated rats, mice, hamsters, and rabbits. We use an Impedence Meter for determining the stage of estrus in rats prior to breeding. Time mated rats and mice are determined by observation of a vaginal plug.

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Nude Mice - More than What Meets the Naked Eye

Laboratory Animals: Origin of Nude Mouse | Nature

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. A Nature Research Journal.

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Laboratory Animals: Origin of Nude Mouse

A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus , resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype main outward appearance of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response. These xenografts are commonly used in research to test new methods of imaging and treating tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene.

Sign in Sign up. Laboratory Mice and Rats. A summary and overview of the mice and rats used in biomedical research, based on a survey of formal publications. Sprague-Dawley and Wistar are the main rat strains.